METABOLIC EFFECTS OF THYROID HORMONES IN VITRO
نویسندگان
چکیده
منابع مشابه
Metabolic effects of thyroid hormones in vitro. II. Influence of thyroxine and triiodothyronine on oxidative phosphorylation.
Because of the profound effect of thyroxine on the metabolic rates of animals, several groups of investigators have sought a relationship between this hormone and oxidative phosphorylation (14). The work in this laboratory was designed to test the hypothesis that the thyroid hormone may exert its salutary effects by uncoupling an oxidative phosphorylation just prior to a rate-limiting step in t...
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The prevalence of metabolic syndrome worldwide is high and rising (Alexander Diabetes 52: 1210, 2003; Cameron Endocrinol Metab Clin North Am 33: 351, 2004). According to all definitions visceral obesity, increased triglycerides, decreased HDL cholesterol, impaired glucose tolerance and increased blood pressure are part of the definition. Thyroid hormones impact on all these factors. In a large ...
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Recently there has been increased interest in the association between thyroid function and obesity. Based on the notion that triiodothyronine (T3) controls metabolic and energy homeostasis and influences body weight, thermogenesis, lipolysis and metabolism of cholesterol, and that thyroid-stimulating hormone (TSH) via receptors in fat tissue, induces differentiation of preadipocytes in to adipo...
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BACKGROUND Clustering of various metabolic parameters including abdominal obesity, hyperglycaemia, low high-density lipoprotein cholesterol, elevated triglycerides and hypertension have been used worldwide as metabolic syndrome to predict cardiometabolic risk. Thyroid dysfunction impacts on various levels of these components. OBJECTIVES The purpose of the present review is to summarize availa...
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Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormone deficiencies, as well as excesses, are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics. Thyroid hormones upregulate the expression of the sarcoplasmic reticulum calcium-activated ATPase and downregulate the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1953
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)66151-4